A trial-and-error process for folding proteins correctly

Proteins are folded in three-dimensional space to properly function. However, in case the folding of the structure right after protein synthesis went wrong, evolution came up with a strategy to give it another try.

In 10 seconds? Protein misfolding can lead to severe diseases including ALS, Parkison’s disease and Alzheimer’s disease. Researchers have now identified a mechanism by which cells can give proteins a new try to fold correctly.